Breast Cancer
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Tucatinib plus letrozole and palbociclib was well-tolerated and active in patients with HR and HER2-positive metastatic breast cancer, according to interim data presented at the SABCS Annual Meeting.
IPATunity130 trial data showed that adding ipatasertib to paclitaxel did not improve PFS in patients with PIK3CA/AKT1/PTEN-altered TNBC.
True or false: Paclitaxel improved PFS and OS compared to capivasertib plus paclitaxel for metastatic triple-negative breast cancer.
True or false: PIK3CA mutations in breast cancer are not accurately detected using ctDNA versus tumor tissue.
The FDA has approved pembrolizumab combined with chemo for the treatment of locally recurrent unresectable or metastatic TNBC.
Use of hormone-modulating therapy for breast cancer was tied to a significant decrease in the number of patients diagnosed with neurodegenerative disease.
Capivasertib in combination with paclitaxel yielded longer PFS and OS in patients with metastatic TNBC, particularly those with PIK3CA/AKT1/PTEN-altered tumors.
True or false: PIK3CA mutations in breast cancer can be accurately detected using ctDNA.
True or False: In patients with previously-treated, ERBB2+, metastatic breast cancer, adding capecitabine to T-DM1 improved outcomes over T-DM1 alone.

News

Tucatinib plus letrozole and palbociclib was well-tolerated and active in patients with HR and HER2-positive metastatic breast cancer, according to interim data presented at the SABCS Annual Meeting.
IPATunity130 trial data showed that adding ipatasertib to paclitaxel did not improve PFS in patients with PIK3CA/AKT1/PTEN-altered TNBC.
The FDA has approved pembrolizumab combined with chemo for the treatment of locally recurrent unresectable or metastatic TNBC.
Use of hormone-modulating therapy for breast cancer was tied to a significant decrease in the number of patients diagnosed with neurodegenerative disease.

Interactive Features

True or false: Paclitaxel improved PFS and OS compared to capivasertib plus paclitaxel for metastatic triple-negative breast cancer.
True or false: PIK3CA mutations in breast cancer are not accurately detected using ctDNA versus tumor tissue.
True or false: PIK3CA mutations in breast cancer can be accurately detected using ctDNA.
True or False: In patients with previously-treated, ERBB2+, metastatic breast cancer, adding capecitabine to T-DM1 improved outcomes over T-DM1 alone.
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